benzamide, 2,4-difluoro-N-methoxy-N-methyl-

benzamide, 2,4-difluoro-N-methoxy-N-methyl- - Names and Identifiers

Name	2,4-DIFLUORO-N-METHOXY-N-METHYLBENZAMIDE
Synonyms	2,4-Difluoro-N-methoxy-N-methylbenzamide 2,4-DIFLUORO-N-METHOXY-N-METHYLBENZAMIDE Benzamide, 2,4-difluoro-N-methoxy-N-methyl- benzamide, 2,4-difluoro-N-methoxy-N-methyl-
CAS	198967-25-8
InChI	InChI=1/C9H9F2NO2/c1-12(14-2)9(13)7-4-3-6(10)5-8(7)11/h3-5H,1-2H3

benzamide, 2,4-difluoro-N-methoxy-N-methyl- - Physico-chemical Properties

Molecular Formula	C9H9F2NO2
Molar Mass	201.17
Density	1.261g/cm³
Boling Point	305.6°C at 760 mmHg
Flash Point	138.6°C
Vapor Presure	0.000815mmHg at 25°C
Storage Condition	2-8°C
Refractive Index	1.493

benzamide, 2,4-difluoro-N-methoxy-N-methyl- - Introduction

2. It is an organic compound with the chemical formula C9H8F2NO2. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: 2, colorless to light yellow crystalline powder or particles.
-Melting point: about 78-81 ° C.
-Boiling point: About 265-267 ° C.
-Solubility: Soluble in most organic solvents, such as benzene, methanol and dichloromethane, insoluble in water.

Use:
- 2, commonly used as pharmaceutical intermediates, plays an important role in the synthesis process.
-It can be used to synthesize various drugs, such as certain antiviral, antibacterial, antitumor and antidepressant drugs.

Method:
2, is usually synthesized by the following steps:
-First, benzoyl chloride is reacted with N-methylformamide to generate N-methyl-N-formylbenzamide.
-Then, under certain conditions, 2,4-difluoroaniline and methanol are added to the reaction product in the previous step, and a nucleophilic substitution reaction occurs to generate 2.

Safety Information:
- 2, is an organic compound, which should be stored and handled in accordance with the safe operating procedures of the chemical laboratory.
-When using, avoid direct contact with skin and eyes, and avoid inhaling gas or dust.
-For accidental contact or misuse, rinse immediately with plenty of water and seek medical attention.
-Be careful to use protective gloves, goggles and laboratory ventilation during handling to ensure safe operation.

Last Update：2024-04-09 21:01:54